The above suggested air changes per hour are only a design rule of thumb.
Clean room design guide.
A basic clean room.
Basic clean room requirements designs for gmp clean rooms what is a clean room.
A clean room explained in simple terms.
They should be computed by an hvac cleanroom expert as many aspects must be taken into consideration such as the size of the room the number of people in the room the equipment in the room the processes involved the heat gain etc.
Cleanroom design in select industries prepared under ashrae technical committee 9 11 clean spaces ashrae design guide for cleanrooms is the culmination of the years long work of subject experts from around the world.
The properly locating of where the air is brought in and taken out is the key to good cleanroom design.
This design is generally thought to be the one to use for the optimum clean room but requires very stringent cleaning techniques done continually as part of the operating process in addition to specialized cleaning performed for each area in the cleanroom.
Other posts about clean rooms.